The present invention relates to a medicament delivery device comprising a distal housing part (12) a proximal housing part (10) into which a multi-chamber medicament container (14) is arranged and wherein said proximal housing part is arranged to be movable in relation to said distal housing part for mixing at least two substances arranged inside said container a plunger rod (32) arranged to act on a distal stopper (34) in said medicament container, wherein a relative movement of said housing parts (10, 12) towards each other forces said distal stopper against the plunger rod in a proximal direction for mixing at least two substances arranged inside said container a drive force unit (58, 74, 76, 78) capable of forcing said plunger rod (32) in the proximal direction for subsequent delivery of medicament from said medicament container an activation member (80) slidably arranged through said distal housing part and releasibly connected to the drive force unit wherein said device further comprises a guide shell (24) one-way rotatable arranged in said distal housing part, wherein said guide shell is provided with threads (22) arranged to cooperate with corresponding threads (20) on said proximal housing, and wherein said guide shell and said plunger rod are arranged with guide members such that they are rotationally locked but slidable in relation to each other.一種藥物輸送裝置,係包括一末端外殼部(12);一近端外殼部(10),一多室藥物容器(14)於其內,在此該近端外殼部可相對於該末端外殼部移動,以混合該容器內的至少兩物質;一柱塞桿(32)作用於末端瓶塞(34)於該藥物容器內,藉此該外殼部(10、12)向彼此相對移動迫使該末端瓶塞倚著柱塞桿向近端移動,以混合該容器內的至少兩物質;一驅動力組件(58、74、76、78)能夠迫使該柱塞桿(32)向近端移動,以隨之從該藥物容器輸送藥物;一啟動構件(80)可滑動地穿過該末端外殼部,且可鬆開地連接於該驅動力組件;在此該裝置更包括一導流桶(24),可單向旋轉於該末端外殼部內,在此該導流桶備有螺紋(22),與該近端外殼上相應之螺紋(20)合作,且在此該導流桶和該柱塞桿備有引導構件以便旋轉地鎖住,但可相對地滑動。10‧‧‧近端外殼部12‧‧‧末端外殼部14‧‧‧藥物容器16‧‧‧頸部18‧‧‧操作構件24‧‧‧導流桶32‧‧‧柱塞桿46‧‧‧鎖件58‧‧‧驅動螺帽64‧‧‧環狀向近端壁架74‧‧‧驅動構件76‧‧‧劑量設定鈕78‧‧‧扭轉驅動彈簧80‧‧‧啟動構件82‧‧‧環狀構件86‧‧‧回位彈簧
