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Solubilized topoisomerase poisons
专利权人:
Edmond J. LaVoie;Leroy F. Liu;Alexander L. Ruchelman
发明人:
Edmond J. LaVoie,Alexander L. Ruchelman,Leroy F. Liu
申请号:
US12851370
公开号:
US08389721B2
申请日:
2010.08.05
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides compounds of formula I:whereinA, B, W, Y, Z, and R1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.
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