Benjamin T. Ewing,Gregory G. Brucker,Scott A. Bednar,John R. Periard,Ashok A. Sharma,Steven D. Savage,Arthur E. Uber, III,Brian P. Dickerson
申请号:
US12990157
公开号:
US09126025B2
申请日:
2009.05.01
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Various methods for optimizing coating of medical devices, such as balloon catheters are disclosed. One method configures catheter balloon folds based on balloon diameter and volume. Other methods include using a specifically-sized protective sheath, using a vacuum, using pressure, pulling the balloon through a coating solution, using at least one spacer or a wick between at least one fold for metering a therapeutic coating into the folds of the balloon, placing an intermediate layer between the balloon and the therapeutic coating, placing a soluble film having a therapeutic agent around the catheter balloon or inside the folds, and any combination thereof. Balloon catheters and catheter balloons having a specific folding configuration, a specifically-sized protective sheath, an intermediate layer, or a soluble film are also disclosed.