Axelrod, Fumiko Takada,Hoey, Timothy Charles,Bruhns, Maureen Fitch,Gurney, Austin L.
申请号:
AU2009269096
公开号:
AU2009269096B9
申请日:
2009.07.08
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Means and methods for the diagnosis, characterization, prognosis and treatment of cancer, specifically targeting cancer stem cells are disclosed Provided is an antibody that specifically binds to a non-ligand binding membrane proximal region of the extracellular domain of a human Notch receptor and inhibits tumor growth, and a method of treating cancer comprising administering said antibody to a subject.