Structures and methods for attaching a device to a users skin are provided. Embodiments include refreshing an adhesive attaching an element of an analyte monitoring device so that a first adhesive attaches the element of the analyte monitoring device during a first time period and a second adhesive attaches the element of the analyte monitoring device to the users skin during a second time period. A sensor remains at least partially inserted into the users while the refreshing of the adhesive from the first to the second adhesive occurs.