Oxidized proteins, their biological activity, and therapeutic and diagnostic measures, which are derived from the active mechansim, from the use of these porteins or from the inhibition thereof
HAMBURGER STIFTUNG ZUR FORDERUNG VAN WISSENSCHAFTUND KULTUR
发明人:
KEHREL BEATE
申请号：
AP200904857
公开号：
AP2781A
申请日:
2001.10.19
申请国别(地区):
AP
年份:
2013
代理人:
摘要：
Medicaments (A and B) for use in humans or animals are new. (A) contains an agent (I) which inhibits the binding of oxidized proteins to CD36 or the functions of CD36 induced by oxidized proteins. (B) contains at least one oxidized protein (II) or oxidized peptide (or a structural analog or mimetic) : An independent claim is included for the preparation of oxidized proteins/peptides, involving reaction with hypochlorous acid or peroxynitrites. ACTIVITY : Anticoagulant； Thrombolytic； Antiinflammatory； Immunosuppressive； Antiarteriosclerotic； Hypotensive； Nephrotropic； Vasotropic； Cardiant； Cerebroprotective； Antidiabetic； Vulnerary； Antibacterial； Anti-HIV； Cytostatic； Antirheumatic； Antiarthritic； Antiulcer； Dermatological. MECHANISM OF ACTION : CD36 antagonist； CD36 agonist.
