TAN, PHILIP,SIMON, SANDY ALEXANDER,CERVENY, CHARLES G.,NILSSON, CHRISTY ANNE,BRADY, WILLIAM,LEDBETTER, JEFFREY A.,HAYDEN-LEDBETTER, MARTHA SUSAN,THOMPSON, PETER ARMSTRONG,MORALES, CECILE
申请号:
CA2719924
公开号:
CA2719924C
申请日:
2009.04.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present disclosure provides a humanized anti-CD37 small modularimmunopharmaceutical (SMIP) molecule,as well as synergistic combination therapies of CD37-specific bindingmolecules (such as anti-CD37 SMIP proteins or antibodies)with bifunctional chemotherapeutics (such as bendamustine) that can beadministered concurrently or sequentially, for use intreating or preventing B cell related autoimmune, inflammatory, orhyperproliferative diseases.