The invention relates to the use of a combination of cannabinoids, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), in the manufacture of a medicament for use in the treatment of cancer. In particular the cancer to be treated is a brain tumor, more particularly a glioma, more particularly still a glioblastoma multiforme (GBM).本發明係有關於尤其是四氫大麻酚(THC)與大麻二酚(CBD)之一種大麻素組合物在製造用於治療癌症的一藥物之用途。尤其,待治療的癌症係一種腦腫瘤,更詳細地係一種神經膠質瘤,又更詳細地係一種多形性神經膠質母細胞瘤(GBM)。