A dry powder inhaler is provided herein having a powder housing defined on an exterior by a generally cylindrical wall. Within the interior volume of the wall, a central passageway is provided through which certain components of the dry powder inhaler may pass. In addition, a powder reservoir is defined within the interior volume having a generally crescent-shaped profile formed along a substantial length of the wall. The powder reservoir terminates at end points between which is defined an isolated inhalation channel. With the configuration provided herein, the powder reservoir has a substantial working length exposed at its bottom to permit removal of medication therefrom. Advantageously, with this configuration, a relatively large amount of medication may be maintained, and obtained access to, in the powder reservoir.