PROBLEM TO BE SOLVED: To provide an alveolar bone resorption inhibitor having an alveolar bone resorption inhibitory effect, and an alveolar bone resorption-related protein expression regulator that regulates the expression of protein involved in the onset mechanism of alveolar bone resorption.SOLUTION: The present invention provides an alveolar bone resorption inhibitor, an osteoprotegerin expression promoter, or an NFκB activating receptor ligand expression inhibitor, containing a niacin compound as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】歯槽骨の吸収に対する抑制効果を有する歯槽骨吸収抑制剤、及び歯槽骨吸収の発症機構に関与するタンパク質の発現を調整する歯槽骨吸収関連タンパク質の発現調整剤を提供する。【解決手段】ナイアシン化合物を有効成分とする、歯槽骨吸収抑制剤、オステオプロテゲリン発現促進剤、又はNFκB活性化受容体リガンド発現抑制剤。【選択図】なし
