Amedical operation support system 100A includes the light source 11, the imaging unit 12, the control unit 2, and the projecting unit 13. The light source 11 applies light of a predetermined wavelength band including the excitation light to the affected part 105. The imaging unit 12 captures a fluorescent image resulting from the fluorescence emission of the affected part 105. The control unit 2 generates the image data for projection based on the fluorescent image captured by the imaging unit 12. The projecting unit 13 projects the projection image based on the image data for projection onto the affected part 105 with visible light. In the medical operation support system 100A, the imaging optical axis Z2 of light incident on the imaging unit 12 is adjusted to be matched with the projection optical axis Z3 of light exiting from the projecting unit 13.
