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Glycoproteins produced in plants with suppressed expression of beta 1, 2-xylosyltransferase
专利权人:
发明人:
申请号:
EP05108014.1
公开号:
EP1621633B1
申请日:
2001.03.02
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Recombinant glycoproteins, obtainable by a method wherein the recombinant glycoproteins are expressed in plants or in cells, wherein the expression of ²1, 2-xylosyltranferase is suppressed or completely blocked so that the peptide sequence of the glycoprotein has less than 50%, particulary less than 20%, particularly 0% of ²1, 2-bound xylose residues present in proteins expressed in non-xylosyl-transferase reduced plant systems. Preferably, said recombinant glycoprotein is characterized in that it is a human protein, especially a human protein for medical use.
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