Laboratoire Francais du Fractionnement et des Biotechnologies
发明人:
Chevreux, Guillaume,Bihoreau, Nicolas
申请号：
AU2014230134
公开号：
AU2014230134A1
申请日:
2014.03.14
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention lies in the technical field of antibody therapies involving a mechanism of target-cell destruction by ADCC. It relates to purified antibody compositions, obtained by chromatographic fractionation of the various charge isoforms naturally present in an antibody composition and combining one or more chromatographic fractions corresponding to the predominant peak of the chromatogram, the resulting monoclonal antibody composition being enriched in said predominant peak, said peak representing at least 85% of the chromatogram of the composition obtained, for use as a medicament.
