PAUL LAIDLER,RODERICK PETER HAFNER,PASCAL HICKEY,MARK LARCHE
申请号：
MX2014014461
公开号：
MX2014014461A
申请日:
2013.05.30
申请国别(地区):
MX
年份:
2015
代理人:
摘要：
Pharmaceutical formulations,which may be used for preventing or treating allergy to moulds of the Alternaria and/or Cladosporiumgenus, comprising a pharmaceutically acceptable carrier or diluent and a polypeptide or a pharmaceutically acceptable salt thereof selected from at least three of: (a)a polypeptide comprising the amino acid sequence of WSWKIGPAIATGNT(Alt28 SEQ ID NO: 101) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof (b)a polypeptide comprising the amino acid sequence of KYRRVVRAGVKVAQTAR(Alt34A SEQ ID NO: 107) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof (c) a polypeptide comprising the amino acid sequence of KYAGVFVSTGTLGGG (SEQ ID NO: 112) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof (d)a polypeptide comprising the amino acid sequence of AEVYQKLKALAKKTYGQ(Alt13A SEQ ID NO: 83) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof (e)a polypeptide comprising the amino acid sequence of SLGFNIKATNGGTLD(Alt01A SEQ ID NO: 60)or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof (f) a polypeptide comprising the amino acid sequence of SAKRMKVAFKLDIEK(Alt06 SEQ ID NO: 72) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof (g)a polypeptide comprising the amino acid sequence of DITYVATATLPNYCR(SEQ ID NO: 111) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof and (h)a polypeptide comprising the amino acid sequence of GWGVMVSHRSGET(Alt14SEQ ID NO: 84) or a T cell epitope-containing variant sequence derived from said amino acid sequence, or a said salt thereof wherein a T cell epitope-containing variant sequence of a said amino acid sequence is said
