Liquid drug transfer assemblies (100A) for use with a drug vial (20) having a drug vial opening (23) stopped by a drug vial stopper (24). The liquid drug transfer assemblies (100A) include a drug vial stopper puncturing member (110) for puncturing a drug vial stopper (24). The liquid drug transfer assemblies (100A) also include a drug vial adapter (120) having a drug vial adapter skirt (122) an upright drug vial adapter port (124) and a drug vial adapter sleeve (131) downward depending opposite the upright drug vial adapter port (124) and in flow communication therewith. The drug vial adapter (120) is slidingly disposed on the drug vial stopper puncturing member (110) such that on mounting the liquid drug transfer assembly (100A) on the drug vial (20) the drug vial stopper puncturing member (110) punctures the drug vial stopper (24) to form a throughgoing puncture bore P and the drug vial adapter sleeve (131) lines the puncture bore P.