A multi-synchronization power supply and an ultrasound system with the same are disclosed. The multi-synchronization power supply includes a microprocessor configured to receive frequency information indicative of a plurality of frequencies and to output a control signal based on the frequency information； a clock signal generating unit configured to receive a reference synchronization clock signal and to generate a plurality of synchronization clock signals corresponding to the plurality of frequencies by frequency-dividing the reference synchronization clock signal based on the control signal； and a plurality of DC-DC converters configured to receive the plurality of synchronization clock signals and a reference DC voltage, and to generate a plurality of DC voltages from the reference DC voltage based on the plurality of synchronization clock signals.
