Identification, optimization and use of immunotherapy for shared HLA-B * 0702 epitopes

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专利权人:

ヴァクソン バイオテック

发明人:

コスマトプロス，コスタンティノス（コスタス）,メネ－ジャメ，ジャンヌ,コスマトプロス,コスタンティノス(コスタス),メネ-ジャメ,ジャンヌ

申请号：

JP2015042488

公开号：

JP6255360B2

申请日:

2015.03.04

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide novel methods and materials for efficiently treating patients having an HLA-B0702 phenotype, based on peptides representing shared epitopes of tumor antigens.SOLUTION: The invention relates to a method for identifying an HLA-B0702 restricted peptide which can induce a cytotoxic response against several antigens from one single multigenic family, to several such epitopes, to a method for producing the HLA-B0702 restricted peptide which can induce cytotoxic response, to an isolated nucleic acid molecule, and to a pharmaceutical composition which is a vaccine.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/