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SYNTHETIC DIBLOCK COPOLYPEPTIDE HYDROGELS FOR USE IN THE CENTRAL NERVOUS SYSTEM
专利权人:
The Regents of the University of California
发明人:
Timothy J. Deming,Michael V. Sofroniew,Chu-Ya Yang,BingBing Song,Yan Ao
申请号:
US14182983
公开号:
US20140286865A1
申请日:
2014.02.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention relates, e.g., to a composition suitable for administration to the central nervous system (CNS), comprising a block copolypeptide hydrogel, which comprises a biologically active material that is mixed with the hydrogel or that is attached to the polypeptide chain of the hydrogel, wherein the composition is suitable for administration to the CNS. Also disclosed are methods of making and using compositions of the invention as depots or as scaffolds for cell migration, and pharmaceutical compositions and kits for implementing methods of the invention.
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