THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)
发明人:
JEONG, HYE GWANG,정혜광,KIM, HYUNG GYUN,김형균,NA, MIN KYUN,나민균
申请号：
KR1020130036604
公开号：
KR1013226640000B1
申请日:
2013.04.04
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: An anticancer composition comprising mollugin is provided to use as a therapeutic agent for cancer patients who have tolerance to existing anticancer drugs by having an excellent effect of killing multidrug resistance cancer cells. CONSTITUTION: An anticancer composition having an effect of killing multidrug resistance cancel cells comprises mollugin of chemical formula 1. The multidrug resistance cancer cells are cancer cells which express multidrug resistance 1 (MDR1). The composition increases activation of AMP-activated protein kinase (AMPK). An anticancer drung is added to the composition. The mollugin is comprised in the composition in a ratio of 0.001-99 wt%.본 발명은 몰루긴을 함유하는 항암용 조성물에 관한 것으로서, 상기 조성물은 다약제 내성 암세포들을 사멸하는 효과가 우수하여, 기존의 항암제에 내성이 생긴 암환자들에 대한 치료제로 유용하게 사용될 수 있다.
