The present disclosure provides copolymers useful in medical devices. For example, the disclosure provides copolymers comprising the polymerization product ester block, ether blocks and diisocyanates. In certain embodiments, the disclosure provides a medical copolymer for implantation comprising ester blocks and ether blocks, wherein: the ester blocks comprise a negative free energy transfer and the ether blocks comprise a positive free energy transfer, theether and ester blocks are less than 1/10 the length of said copolymer, and, the blocks are distributed such that no domain of contiguous blocks possessing the same polarity of free energy transfer are less than 1/3 of the molecular weight of the copolymer. The disclosure further provides methods of making the aforementioned polymers, and medical devices comprising the polymers.本揭示提出可用於醫療裝置之共聚物。例如,本揭示提出包含聚合產物酯嵌段、醚嵌段及二異氰酸酯之共聚物。在特定具體實例中,本揭示提出包括酯嵌段及醚嵌段之用於植入的醫療共聚物,其中:該等酯嵌段包含負自由能轉移且該等醚嵌段包含正自由能轉移,該等醚及酯嵌段小於該共聚物1/10長度,且該等嵌段係分布使得沒有任何具有相同自由能轉移極性的相連嵌段區間小於該共聚物分子量之1/3。本揭示另外提出製造上述聚合物之方法及包含該等聚合物之醫療裝置。100‧‧‧手術阻隔物102‧‧‧抗黏著表面104‧‧‧細胞傳導層106‧‧‧結構表面108‧‧‧梯狀結構110‧‧‧連接部分112‧‧‧穿孔
