BIORESTORATIVE THERAPIES INC.;FRANCISCO JAVIER SILVA
发明人:
FRANCISCO JAVIER SILVA
申请号:
IL24215015
公开号:
IL242150A
申请日:
2015.10.18
申请国别(地区):
IL
年份:
2020
代理人:
摘要:
An isolated human brown adipose tissue stem cell line. In one embodiment, the isolated human brown adipose tissue stem cell line expresses the markers CD9, SSEA4, CD44, CD90, CD166, CD73, but not CD14, CD34, CD45 or STRO-1. In another embodiment, the isolated human brown adipose tissue stem cell line expresses the genes UCP1, PPARGC1A, NRF1, FOXC2, CREB1, SIRT3, and WNT5A (REFX). In still another embodiment, the isolated human brown adipose tissue stem cell line is capable of differentiating into osteoblasts, chondrocytes, and adipocytes.