HENROTIN, YVES,SANCHEZ, CHRISTELLE,OPRENYESZK, FRÉDÉRIC,DRION, PIERRE
申请号：
SG2012061131
公开号：
SG183379A1
申请日:
2011.02.11
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
A method of producing a hydrogel for intra-articular supplement comprising the steps of: - providing a solution of alginate, - providing a solution with chitosan having a Mw between lower than 60 kD, - mixing the solution of alginate and the solution of chitosan, wherein the mixed solution comprises between 0.5 and 0.7 % (w/v) of chitosan and between 1 and 1.4 % alginate (w/v), - introducing droplets of the mixed solution into a solution with Ca2+ or Sr2+ cations and - isolating polymerised beads from the solution with cations
