An ambulatory medical device capable of delivering therapy to a patient includes at least one response mechanism having a state capable of being activated by one response button； a controller operatively connected with the at least one response mechanism, the controller including at least one processor coupled with a memory； and a therapy manager component executable by the controller and configured to detect a physiological parameter having a value indicative of a health disorder of the patient, notify the patient of impending therapy delivery in response to the detection of the physiological parameter, monitor the state of each at least one response mechanism within at least one predetermined time period, and delay therapy delivery to the patient in response to detection of a change in the state in a single response mechanism of the at least one response mechanism within the at least one predetermined time period.
