The Research Foundation of State University of New York;Baxter International Inc.;Brookhaven Science Associates, LLC;Baxter Healthcare S.A.
发明人:
Crowe, Brian A.,Livey, Ian,O'Rourke, Maria,Schwendinger, Michael,Dunn, John J.,Luft, Benjamin J.,ORourke, Maria
申请号：
AU2011252850
公开号：
AU2011252850B2
申请日:
2011.05.13
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The invention relates to the development of chimeric OspA molecules for use in against Lyme disease or borreliosis vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies.
