Manufacture of vaccines that contain both hepatitis B virus surface antigens and surfactant

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专利权人:

Mario Contorni

发明人:

Mario Contorni

申请号：

US13302279

公开号：

US08802111B2

申请日:

2011.11.22

申请国别(地区):

US

年份:

2014

代理人:

摘要：

When preparing HBsAg for use in a combination vaccine, it us known to add a non-ionic detergent after the HBsAg has been purified. Adding detergents after purification of HBsAg is not optimal, however, as it requires a separate processing step during manufacture. Thus the invention uses them during HBsAg purification.

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