PURPOSE: A cosmetic composition containing embryonic stem cell-derived vascular angiogenic progenitor cell culture or fraction thereof is provided to suppress tyrosinase activity and to ensure excellent skin whitening. CONSTITUTION: A cosmetic composition for skin whitening contains embryonic stem cell-derived vascular angiogenic progenitor cell culture or fraction thereof as an active ingredient. The culture is prepared by a culture, centrifuging embryonic stem cell-derived vascular angiogenic progenitor cells culture medium to obtain supernatant, concentrate of the supernatant, or freeze-dried product of the supernatant. The embryonic stem cell is human embryonic stem cells.본 발명은 배아줄기세포-유래 혈관형성전구세포(embryonic stem cell-derived vascular angiogenic progenitor cells)의 배양물 또는 그의 분획물을 유효성분으로 포함하는, 미백용 화장료 조성물을 제공한다.