This invention relates to an apparatus and method for generating a blood vessel in a three-dimensional in vitro. Angiogenesis device of the present invention is the interaction between the fluid sink and an inlet (fluid communication) to sync channel Interaction between the source inlet and the fluid (fluid communication), and the sync channel in parallel with the source channel, sync channel, and the channel between the source angiogenic interaction between the inlet channel and the fluid (fluid communication), and the sync channel and the source channel one side and the tangent of the source channel and the sync channel in parallel with angiogenesis channel fluid interaction with the first culture channel inlet (fluid communication), and abuts the other side of the sync channel, the sync channel and a parallel The first channel is located in the culture And interaction between the fluid inlet channel and the second culture (fluid communication), and abuts the other side of the source channel, the source includes a channel and the second channel in the culture in parallel, the boundary of each channel are in contact with each other, each a plurality of microstructures, which allow the interaction between the biological material is contained in the channel is arranged with a gap. The invention further step of injecting the extracellular matrix in angiogenesis and angiogenic cell channel of the blood vessel-generating device First culture channel and / or the step of injecting ) extracellular matrix or ) extracellular matrix and co-cultured cells to a second channel of the culture angiogenesis device And injecting the sync channel and / or angiogenic factors to the trigger source (angiogenesis factor) and / or the cell culture medium of the device to provide a blood vessel angiogenesis generation method comprising culturing said cells and angiogenesis co-culture cells .본 발명은 생체 외에서 3차원으로 혈관을 생성하기 위한 장치 및 방법에 관한 것이다.본 발명의 혈관 생성 장치는 싱크유입구와 유체간 상호작용(fluid communication)
