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Mammalian and Bacterial Nitric Oxide Synthase Inhibitors
专利权人:
Northwestern University
发明人:
Richard B. Silverman,Heng-Yen Wang,Yajuan Qin,Fengwei Zou,Soo Sung Kang,Qing Jing
申请号:
US15482210
公开号:
US20170275278A1
申请日:
2017.04.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed are compounds that are shown to inhibit the biological activity of nitric oxide synthases (NOSs). Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds and pharmaceutical compositions for treating a subject in need thereof. Because the disclosed compounds are shown to inhibit the activity of nitric oxide synthases (NOSs), the disclosed compounds and pharmaceutical compositions may be utilized in methods for treating a subject having or at risk for developing a disease or disorder that is associated with NOS activity.
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