A device for sealing a fistula includes a first flange for orienting against afirst wall of the fistula, a second flangefor orienting against a second wall of the fistula, and at least one stemcoupling the first and second flanges. Illustratively, the atleast one stem is elastomeric. The stem(s) exhibit(s) an elongation of greaterthan about.6 mm/N of force applied between the firstand second flanges in the range of elongation of about 0 mm to about 15 mm.Additionally or alternatively illustratively, thestem(s) comprise(s) (an) elastomeric tube(s) including (a) wall section(s)having a varying radius along its (their) length(s). Additionallyor alternatively illustratively, the stem(s) pass(es) through (respective)opening(s) provided in at least one of the first andsecond flanges to permit adjustment of the location of at least one of thefirst and second flanges along the length of the stem(s).