UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
发明人:
YOON, SEUNG YONG,윤승용,KIM, DONG HOU,김동호,KIM, IN KI,김인기
申请号：
KR1020110137658
公开号：
KR1020130070371A
申请日:
2011.12.19
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition for preventing or treating neurodegenerative diseases is provided to effectively prevent or treat neurodegenerative diseases, especially Alzheimers disease, and to be used as a pharmaceutical product or a health supplementary food.CONSTITUTION: A pharmaceutical composition for preventing or treating neurodegerative diseases contains one or more selected from the group consisting of 3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine, methyldopa, levodopa, N-methyldopamine hydrochloride, dopamine hydrochloride, methyldopate hydrochloride, hydrochloride, SKF 75670 hydrobromide, SKF 89626, N-allyl-SKF 38393 hydrobromide, SKF 89145 hydrobromide, and SKF 83959 hydrobromide. The pharmaceutical composition additionally contains one or more additives selected from the group consisting of a carrier, an excipient, a disintegrant, a sweetener, a coating agent, an expander, a lubricant, a flavoring agent, an antioxidant, a buffer solution, fungistats, a diluents, a dispersing agent, a surfactant, and a binder.COPYRIGHT KIPO 2013본 발명은 3-(3,4-디하이드록시페닐)-2-메틸-DL-알라닌(3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine), 메틸도파(methyldopa), 레보도파(levodopa), N-메틸도파민 하이드로클로라이드(N-methyldopamine hydrochloride), 도파민 하이드로클로라이드(dopamine hydrochloride), 메틸도페이트 하이드로클로라이드(methyldopate hydrochloride), 3,4-디하이드록시페닐아세트산(3,4-dihydroxyphenylacetic acid), SKF 38393 하이드로클로라이드, SKF 75670 하이드로브로마이드, SKF 89626, N-알릴-SKF 38393 하이드로브로마이드(N-allyl-SKF 38393 hydrobromide), SKF 89145 하이드로브로마이드 및 SKF 83959 하이드로브로마이드로 이루어진 군에서 선택된 어느 하나 또는 둘 이상을 유효성분으로 포함하는 퇴행성 신경질환 예방 또는 치료용 약학 조성물을 제공한다. 본 발명에 따른 조성물은 퇴행성 신경질환, 특히 알츠하이머의 예방 또는 치료효과가 우수하여 의약품 또는 건강 보조 식품으로 유용하게 사용될 수 있다.
