Ronald E. Zimmerman,David John Stokell,Michael Patrick Akers
申请号：
US15007949
公开号：
US10100098B2
申请日:
2016.01.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Novel proinsulins and glargine, aspart and Lis-Pro proinsulin analogs having specific amino acid and/or nucleic acid modifications suitable for improved methods of insulin production, as well as novel and highly efficient processes for preparing the same. The novel proinsulins and proinsulin analogs may be converted into human insulin and insulin analogs, respectively, that are useful in therapeutic preparations.
