A combine harvester comprises a purification device excellent in durability and a grain tank capable of storing a great quantity of grains. A DPF (diesel particulate filter) unit (40) which is used for purifying exhaust of an engine (9) is disposed on a portion, in the bilateral center of a body, of a transverse side of a threshing device (5), and an exhaust manifold (30B) of the engine (9) is connected with a gas inlet (40E) of the DPF unit (40) through flexible connecting pipes (52 and 72). In addition, the DPF unit (40) is disposed between the threshing device (5) and the grain tank (6), the lower portion of the grain tank (6) is provided with an inclined wall (21D) inclined downward towards the outer side of the body, and the DPF unit (40) enters a space of the lower side of the inclined wall (21D).一種聯合收割機,其具備耐久性優良的淨化裝置和能夠儲存大量的谷粒的穀粒箱。為了解決上述課題,在脫粒裝置(5)的橫向側的機體左右方向中央側的部位配置對發動機(9)的排出氣體進行淨化的DPF單元(40),並將上述發動機(9)的排氣歧管(30B)與DPF單元(40)的進氣口(40E)經由有撓性的連接管(52、72)連接。此外,在脫粒裝置(5)和穀粒箱(6)之間配置DPF單元(40),在穀粒箱(6)的下部設置朝著機體外側向下傾斜的傾斜壁(21D),使上述DPF單元(40)進入該傾斜壁(21D)的下側的空間。