Sung Won LEE,Jong Kwan PARK,In Suk SO,Hyun Hwan SUNG,Jae Il KIM,Young Chul KIM,Jin Seok PARK
申请号：
US14994382
公开号：
US20160235710A1
申请日:
2016.01.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a pharmaceutical composition for treating or preventing erectile dysfunction, containing LDD175 as an active ingredient. Furthermore, the present invention relates to a co-administration preparation for treating or preventing erectile dysfunction, containing LDD175 and a PDE5 inhibitor as active ingredients. The LDD175 of the present invention has an excellent corporal smooth muscle relaxation effect, and thus significantly improved erectile function. Since the LDD175 of the present invention acts on BKCa channels, and thus is expected to have little adverse cardiovascular effects. The LDD175 of the present invention exhibits an erectile dysfunction therapeutic ability equivalent to that of udenafil, which is a PDE5 inhibitor, and showed a synergistic corporal smooth muscle relaxation effect when being co-administered with udenafil.
