The present invention is directed towards various topicalprotective formulations, which may be used as an adjunct inpreventing the spread of a broad range of sexually transmitteddiseases. The product is intended to be used as a topicallotion, cream, emulsion, or the like. The film formingexcipients and active ingredients in the following formulationshave demonstrated unique skin protective barrier properties withenhanced persistence that inhibits transmission of sexuallytransmitted diseases.