Nitin DHARMADHIKARI,Yashoraj ZALA,Abhishek JAIN,Bramhanand HANAMANNAVAR,Umesh PAI
申请号:
US16625271
公开号:
US20200222329A1
申请日:
2018.06.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
An abuse deterrent oral solid dosage form comprising:an inner portion comprising a drug susceptible to abuse and a pH dependent polymer soluble in acidic mediuman outer portion, wherein the portion is devoid of drug susceptible to abuse and comprises an immediate release form of alkalizer and a sustained release form of alkalizer, the sustained release form of alkalizer comprising an alkalizer and a rate controlling excipient.