An endoscope system comprising: an endoscope (104) having an instrument channel having an inner diameter； and an anchoring assembly (406) including an inflatable/deflatable balloon assembly (430) comprising a catheter and at least one balloon (434) arrangeable, when deflated, in a first orientation along a deflated balloon axis (446) and arrangeable by virtue of its being inflated, in a second asymmetrically shaped orientation along an inflated balloon axis, tilted with respect to said deflated balloon axis (446).
