ШИРВАН Анат (IL),ТЕЛЕМАН Дан (IL),АРАД Гила (IL),КЭМПФЕР Раймонд (IL)
申请号：
RU2014133530
公开号：
RU2014133530A
申请日:
2013.01.16
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A peptide consisting of the amino acid sequence SPMLVAYD, designated SEQ ID NO: 1, also designated as p2TA, or a derivative thereof, consisting of the amino acid sequence (DA) SPMLVAYD (DA), designated SEQ ID NO: 2, also designated as D-Ala-p2TA, or any functional derivative, fragment, salt or ester of the indicated peptide for use in a method of treating at least one of: an infection and associated acute inflammation, in a person in need of such treatment, wherein said peptide is administered the specified subject in TWO from 0.025 to 1.0 mg peptide / kg body weight of the specified subject. 2. The peptide for use according to claim 1, characterized in that said at least one of: infection and related acute inflammation is caused by at least one of gram-positive bacteria, gram-negative bacteria, polymicrobial infection, bacterial toxins and other toxic bacterial components. 3. A peptide consisting of the amino acid sequence SPMLVAYD, designated SEQ ID NO: 1, also designated p2TA, or a derivative thereof, consisting of the amino acid sequence (DA) SPMLVAYD (DA), designated SEQ ID NO: 2, also designated D- Ala-p2TA, or any functional derivative, fragment, salt or ester of this peptide, for use in a method, the goal of which is to achieve at least one of: preventing deterioration, stopping and reducing damage resulting from or associated with at least about days from: infection and related acute inflammation caused by at least one of gram-positive bacteria, gram-negative bacteria, polymicrobial infection and bacterial toxins in a person in need thereof,1. Пептид, состоящий из последовательности аминокислот SPMLVAYD, обозначенной как SEQ ID NO: 1, также обозначенной как p2TA, или его производное, состоящее из последовательности аминокислот (D-A)SPMLVAYD(D-A), обозначенной как SEQ ID NO: 2, также обозначенной как D-Ala-p2TA, или любое функциональное производное, фрагмент, соль или сложный эфир указанного пептида для применения в способе лечения по меньшей мере одного
