Susan L. Lindquist,Tiago Outeiro,Richard Labaudinière
申请号:
US11575481
公开号:
US08440705B2
申请日:
2005.09.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles.