summary "pyrrolobenzodiazepines" a compound of formula i: wherein: r2 is of formula ii: where a is an aryl group c5-7, x is selected from the group comprising: nhnh2, conhnh2,,, and: q1 is a single bond, and q2 is selected from a single bond and -z- (ch2) n-, where z is selected from a single bond, o, if nh and n is from 1 to 3； or q1 is -ch = ch-, and q2 is a single bond； R 12 is a C 5-10 aryl group, optionally substituted by one or more substituents selected from the group comprising: halo, nitro, cyano, ether, C 1-7 alkyl, C 3-7 heterocyclyl and C 1-3 alkylene； r6 and r9 are independently selected from h, r, oh, or, sh, sr, nh2, nhr, nrr ', nitro, me3sn and halo； where r and r 'are independently selected from optionally substituted c 1-12 alkyl, c 3-20 heterocyclyl and c 5-20 aryl groups； r7 is selected from h, r, oh, or, sh, sr, nh2, nhr, nhrr ', nitro, me3sn and halo； or: r10 is h, and r11 is oh, now where r is C1-4 alkyl； R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are attached； or r10 is h and r11 is alone, where z is 2 or 3 and m is a pharmaceutically acceptable monovalent cation； R 'is a C 3-12 alkylene group whose chain may be interrupted by one or more heteroatoms, and / or aromatic rings； y and y 'are selected from o, s, or nh； r6 ', r7', r9 'are selected from the same groups as r6, r7 and r9 respectively and r10' and r11 'are the same as r10 and r11, where if r11 and r11' are alone, m can represent a divalent cation pharmaceutically acceptable.resumo “pirrolobenzodiazepinas” um composto com a fórmula i: em que: r2 é da fórmula ii: onde a é um grupo arila c5-7, x é selecionado a partir do grupo compreendendo: nhnh2, conhnh2, , , e: q1 é uma ligação única, e q2 é selecionado a partir de uma ligação única e -z-(ch2)n-, onde z é selecionado a partir de uma ligação única, o, s e nh e n é a partir de 1 a 3； ou q1 é -ch=ch-, e q2 é uma ligação única； r12 é um grupo arila c5-10, opcionalmente substituído po
