Quinine-tripyridine-ethylpyridyl methanol derivatives, such as cyclopropyl pyridine isopropylene glycol； preparation process； intermediate compounds； including the components of these compounds, for the treatment of inflammatory or autoimmune diseases, such as multiple sclerosis and lupus； and For the treatment of cancer

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专利权人:

ARRAY BIOPHARMA INC.

发明人:

DELISLE ROBERT KIRK,BLAKE JAMES F,DE MEESE LISA,GRAHAM JAMES M,LE HUEROU YVAN,LYON MICHAEL,ROBINSON JOHN E,WALLACE ELI,WANG BIN,XU RUI

申请号：

CL2013002446

公开号：

CL2013002446A1

申请日:

2013.08.23

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

Compounds of Formula I: in which R1, R2, R3, R4 and R10 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases.COMPUESTOS DERIVADOS DE QUINOLIN-TRIAZOLOPIRIDIN-ETILPIRROLIDINA, COMO INIHIBIDORES DE CINASA PIM； PROCESO PARA SU PREPARACION； COMPUESTOS INTERMEDIARIOS； COMPOSICION QUE LOS COMPRENDE, UTIL PARA EL TRATAMIENTO DE UNA ENFERMEDAD INFLAMATORIA O AUTOINMUNITARIA TAL COMO ESCLEROSIS MULTIPLE Y LUPUS, Y PARA EL TRATAMIENTO DEL CANCER.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/