YOO, DANA SUE,KUANG, JIN-QIANG,PADEN, JAIME,MAXSON, SCOTT A.,DANILKOVITCH, ALLA,LOPEZ, ERASMO,TOM, SAMSON
申请号:
CA2878802
公开号:
CA2878802A1
申请日:
2013.07.11
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
This invention provides disrupted cartilage products, methods of manufacturing disrupted cartilage products, and methods of treating a subject comprising administering a cartilage product. The cartilage products are manufactured by a method comprising disrupting a collagen matrix, e.g. to produce a flexible cartilage product. Optionally, the cartilage products comprise viable chondrocytes, bioactive factors such as chondrogenic factors, and a collagen type II matrix. Optionally, the cartilage products are non-immunogenic.