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Boron trioxide glass-based fibers and particles in dressings, sutures, surgical glue, and other wound care compositions
专利权人:
Delbert E. Day;Steven B. Jung
发明人:
Steven B. Jung,Delbert E. Day
申请号:
US12683244
公开号:
US08173154B2
申请日:
2010.01.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A method and compositions for wound care management comprising a dressing comprising a three-dimensional body of glass-based fibers comprising 40 to 80 weight % B2O3, wherein at least 25 wt. % of the fibers have a diameter between 200 nm and 4000 nm, and a length:width aspect ratio of at least 10. The glasses may also be used for wound care as fibers formed into sutures, as particles in surgical glue to close a wound, or as particles in an ointment or cream to apply to a wound. The compositions may comprise glass formers P2O5 and/or SiO2; alkali oxides selected from Li2O, Na2O, K2O, and Rb2O; and/or alkaline earth oxides selected from MgO, SrO, BaO and CaO. The compositions may further comprise 0.05 to 10 wt. % of one or more trace elements selected from Ag, Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn.
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