PROBLEM TO BE SOLVED: To provide specific and more effective cancer therapies comprising combined administration of effective amounts of an angiogenic factor (VEGF-C) antagonist and an anti-neoplastic composition.SOLUTION: A composite drug comprises: a VEGF-C antibody, which is a VEGF-C antagonist； and an anti-neoplastic composition which contains bevacizumab, which is a VEGF-A antibody, and further contains a chemotherapeutic agent such as docetaxel, 5-fluorouracil, temozolomide, gemcitabine, oxaliplatin, paclitaxel, carboplatin and irinotecan.SELECTED DRAWING: None【課題】有効量の血管新生因子（ＶＥＧＦ－Ｃ）拮抗剤と抗腫瘍性組成物を組みわせて投与する、特異性があってより効果的ながんの治療法の提供。【解決手段】ＶＥＧＦ－Ｃ拮抗剤であるＶＥＧＦ－Ｃ抗体とＶＥＧＦ－Ａ抗体であるベバシズマブに、ドセタキセル、５－フルオロウラシル、テモゾロマイド、ゲムシタビン、オキサリプラチン、パクリタキセル、カルボプラチンおよびイリノテカンなどの化学療法剤をさらに含む抗腫瘍性組成物からなる複合薬。【選択図】なし
