An oral care composition comprising (a) a silica abrasive having an average particle size of no greater than the diameter of a dentin tubule, or, alternatively 8 microns or less; (b) zinc citrate, (c) a bioadhesive agent, and (d) an anticalculus agent. The oral care composition can reduce or inhibit biofilm formation and/or dentinal hypersensitivity in an oral cavity.本發明有關一種口腔護理組成物,包括(a)具有平均粒徑不大於牙本質小管直徑或不大於8微米或更小之矽石磨料、(b)檸檬酸鋅、(c)生物黏著劑、及(d)抗結石劑。該口腔護理組成物可減少或抑制口腔中生物膜形成及/或牙本質過敏症。