DSO National Laboratories;National University of Singapore
发明人:
Macary, Paul Anthony,Teoh, Ee Ping Evelyn,Hanson, Brendon John,Teo, En Wei,Lim, Angeline Pei Chiew,Ng, Mah Lee Mary,Lok, Shee Mei,Kukkaro, Petra Eveliina
申请号:
AU2011341744
公开号:
AU2011341744A1
申请日:
2011.12.14
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.