LIPOSOMES WITH LIPIDS HAVING AN ADVANTAGEOUS PKA- VALUE FOR RNA DELIVERY

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专利权人:

发明人:

GEALL ANDREW

申请号：

IN4161/KOLNP/2012

公开号：

IN2012KN04161A

申请日:

2012.12.28

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and preferably a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation.

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中国工程科技知识中心

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http://www.ckcest.cn/home/