Provided are a portable device and method for non-invasive blood glucose detection, the method comprising the following steps: a signal processing circuit (3) controlling an infrared light source (13) to emit near infrared light to radiate at a portion to be detected of a human body; a photoelectric sensor (14) acquiring, from the portion to be detected of the human body, a pulse wave signal, and sending same to the signal processing circuit (3) for signal pre-processing (S31); acquiring the pulse wave signal from the signal processing circuit (3) (S32), and extracting a feature value of the acquired pulse wave signal (S33); using a neural prediction network to detect the feature value of the pulse wave signal, so as to obtain an original detection value of the blood glucose concentration (S34); using a neural classification network to detect the feature value of the pulse wave signal, so as to obtain a detection range of the blood glucose concentration (S35); determining whether the original detection value is within the detection range (S36); and if the original detection value is within the detection range, displaying the original detection value on a display screen (23) as a blood glucose concentration value of the human body (S37). The method can effectively reduce the disturbance on the blood glucose concentration caused by the other components of human body blood, and can improve the accuracy of the blood glucose concentration detection.La présente invention concerne un dispositif portatif et un procédé de détection non effractive de la glycémie, le procédé consistant : à commander, par un circuit de traitement de signal (3), une source de lumière infrarouge (13) de manière à émettre de la lumière dans le proche infrarouge afin d'exposer au rayonnement une partie à détecter d'un corps humain ; à acquérir, par un capteur photoélectrique (14) depuis la partie à détecter du corps humain, un signal d'onde d'impulsion, et à envoyer ce dernier vers le circuit de tr