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METHOD FOR OBTAINING LEYDIG CELLS BY CARRYING OUT INDUCED DIFFERENTIATION ON HUMAN INDUCED PLURIPOTENT STEM CELLS, AND USE OF LEYDIG CELLS
专利权人:
发明人:
申请号:
EP16868053.6
公开号:
EP3369809A1
申请日:
2016.11.25
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present application provides an in-vitro committed differentiation method for inducing human induced pluripotent stem cells (hiPSCs) into Leydig cells (LCs) by neural crest stem cells (NCSCs). The hiPS-derived LCs is verified by an animal model to have the capacity of regenerating senile or injured LCs, so that a new treatment for supplementing testosterone is provided for patients suffering from hypogonadism, particularly for patients suffering from late-onset hypogonadism (LOH).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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