STEINITZ KATHARINA NORA,WILHELMINA VAN HELDEN PAULA MARIA,REIPERT BIRGIT MARIA,SCHWARZ HANS-PETER,EHRLICH HARTMUT
申请号:
NZ60947411
公开号:
NZ609474A
申请日:
2011.10.27
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is a peptide consisting of the amino acid sequence: (R1)x-P-(R2)y, wherein: P is an amino acid sequence having at least 90% identity to a sequence of SEQ ID NO: 344; R1 is an amino acid sequence consisting of from 1 to 80 amino acids; R2 is an amino acid sequence consisting of from 1 to 80 amino acids; and each of x and y are independently zero or one; wherein SEQ ID NO: 344 is QANRSPLPIAKVSSFPSIRPIYLT. Also disclosed is the use of the peptide for inducing an immune tolerance to FVIII in a subject.