ISMAIL MAHMOUD HAFEZ,RAJEEV KALLANTHOTTATHIL G.,MADDEN THOMAS D.,HOPE MICHAEL J.,MAIER MARTIN A.,CULLIS PIETER,AKINC AKIN,MANOHARAN MUTHIAH,JAYARAMAN MUTHUSAMY
申请号：
NZ60072510
公开号：
NZ600725A
申请日:
2010.12.17
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed is a lipid particle comprising a first cationic lipid, a second cationic lipid, a neutral lipid, and a lipid capable of reducing aggregation wherein the first cationic lipid is selected on the basis of a first property and the second cationic lipid is selected on the basis of a second property., wherein the first property is a measured value of pK. falling within a first range, and the second property is a measured value of pK. falling within a second range, and wherein when the first cationic lipid and the second cationic lipid are combined the measured value of the pK. is no less than 6.1 and no greater than 6.7.
